WASHINGTON: Tainted batches of Russia's Sputnik V COVID-19 vaccine sent to Brazil carried a live version of a common cold-causing virus, the South American country's health regulator reported in a presentation explaining its decision to ban the drug's import.
The issue centres around an"adenovirus vector" - a virus that normally causes mild respiratory illness but in vaccines is genetically modified so that it cannot replicate, and edited to carry the DNA instructions for human cells to develop the spike protein of the coronavirus.The Sputnik V vaccine uses two different adenovirus vectors to accomplish this task: adenovirus type 26 for the first shot, and adenovirus type 5 for the second shot.
"But in people who are immune compromised ... there could be a higher rate of adverse effects because of it, including potentially serious ones." If people aren't sure that the vaccine they are receiving is the same that was studied in trials, then"I can imagine that some people might have their reservations about getting that vaccine at all," said Rasmussen.
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