A US pharmaceutical company behind an experimental Alzheimer’s drug presented new results on Thursday, seeking to restore confidence in the resurrected medicine months after halting clinical trials because it had appeared to have failed.
Biogen presented the new data at a research conference in San Diego and argued that in one of the two trials, an analysis of the data showed its drug aducanumab was, in fact, effective in reducing cognitive decline in patients at a higher dose. The monoclonal antibody aims to dissolve the build-up of a protein, beta-amyloid, in the brain tissue of Alzheimer’s patients. This is one of the three main avenues being explored by researchers against the disease.
The response was mixed among experts in the field, with some welcoming the new data and others cautioning that more scrutiny is required if the drug is to pass regulatory muster with the US Food and Drug Administration .
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