COVID-19: Nigeria records 352 cases Friday as WHO approves new drugs for treatment

15/01/2022 12:21:00 PM

COVID-19: Nigeria records 352 cases Friday as WHO approves new drugs for treatment

COVID-19: Nigeria records 352 cases Friday as WHO approves new drugs for treatment

The WHO panel of experts also looked at two other drugs for severe and critical COVID-19: ruxolitinib and tofacitinib, and gave conditional recommendation against their use

by January 15, 2022 2 min read Nigeria on Friday heaved a little sigh of relief from the rampaging coronavirus pandemic as the country recorded no fresh fatality from the virus and just 352 new infections.A logo is pictured on the headquarters of the World Health Organization (WHO) in Geneva, Switzerland.by January 14, 2022 1 min read For the first time in many days, Nigeria on Thursday recorded no death from the coronavirus pandemic which has claimed many lives consistently in the past few days.Nigeria COVID-19 summit.

Since the announcement of the fourth wave of the pandemic by the Nigeria Centre for Disease Control (NCDC), the country had consistently recorded higher figure of infections and increased fatalities.This is as the World Health Organisation (WHO) has approved two new drugs – baricitinib and sotrovimab – to treat the pandemic.In their recommendation in British medical Journal the BMJ, WHO experts said arthritis drug baricitinib used with corticosteroids to treat severe or critical Covid patients led to better survival rates and reduced need for ventilators.The new drugs are in addition to those earlier approved among other measures introduced to curb the virulence of the disease.With the new infections, the NCDC noted that the infection toll now stands at 250,009, while 221,203 people have been successfully treated and discharged across the country.The WHO disclosed this in a statement published on its website on Friday, noting that the extent to which these medicines will save lives depends on their availability and affordability.Sotrovimab’s benefits for people not at risk of hospitalisation were deemed insignificant and the WHO said its effectiveness against new variants like Omicron was “still uncertain”.Nigeria’s COVID-19 Update The latest statistics released by the NCDC early Saturday morning revealed that the fresh cases were reported across eight states of the federation and the Federal Capital Territory (FCT).In a communiqué issued yesterday in Abuja, the participants observed that Nigeria should enlist the support of African countries in the collaborative process to end the COVID-19 pandemic on the continent and build back stronger public health systems, adding that the current level of engagement with the organised private sector in strengthening the health sector should be encouraged and sustained.

The new cases have raised Nigeria’s infection toll to 250,361, while the fatality toll still stands at 3,092.Corticosteroids are inexpensive and widely available and fight inflammation that commonly accompanies severe cases.Kaduna State reported 21 cases, Oyo, 14; Benue, 11; Cross River, 10; and Kwara State with 9 cases.The data also shows a significant decrease in the number of active cases from over 25,000 cases as of January 13, 2022, to 23, 768 cases on Friday.The disease centre also noted that a total of 223,495 people have been successfully treated and discharged in Nigeria.Baricitinib is in a different class of drugs known as Janus kinase inhibitors, but it falls under the same guidelines as the IL-6 inhibitors.Breakdown The breakdown of the NCDC data revealed that Rivers State topped the infection chart with 119 cases, and is closely followed by Lagos State, the epicentre of the disease, with 106 cases.The NCDC noted that Plateau and Katsina states reported that they recorded no cases on Thursday.While Gombe State ranked third on the log with 50 cases, the FCT followed with 36 cases.Synthetic antibody treatment Regeneron was approved by the WHO in September and the guidelines say Sotrovimab can be used for the same type of patients.Government should strengthen the collaboration between the national and sub-national entities.

Next is Delta and Kaduna states with 16 and 14 cases respectively, while Oyo and Taraba States reported five cases each.Kano State came last on the log with a single case, while the NCDC noted that the duo of Plateau and Sokoto states reported that they recorded no cases on Friday.In this article.The recommended drugs According to WHO, the recommended drugs are based on evidence from seven trials involving more than 4,000 patients with non-severe, severe, and critical COVID-19 infections.It said the first drug, simply identified as baricitinib, is strongly recommended for patients with severe or critical COVID-19 and taken with corticosteroids.The global body said the baricitinib is part of a class of drugs called Janus kinase (JAK) inhibitors that suppress the overstimulation of the immune system.” The institution was, however, optimistic that “Africa vaccinating Africa is necessary” and achievable.

“Baricitinib is an oral drug, used in the treatment of rheumatoid arthritis.It provides an alternative to other arthritis drugs called Interleukin-6 receptor blockers, recommended by WHO in July 2021,” the statement reads in part.It added that the second drug, sotrovimab, has been conditionally recommended for treating mild or moderate COVID-19 in patients who are at the high risk of hospitalisation.READ ALSO: Pfizer, BioNTech apply for EU’s conditional approval of COVID-19 vaccine WHO specified that the patients who can take sotrovimab include older people, immunocompromised, those having underlying conditions like diabetes, hypertension, and obesity, and those unvaccinated.The statement further reads: “Sotrovimab is an alternative to casirivimab-imdevimab, a monoclonal antibody cocktail recommended by WHO in September 2021 “Studies are ongoing on the effectiveness of monoclonal antibodies against Omicron but early laboratory studies show that sotrovimab retains its activity.This need is especially acute given that the overall COVID vaccination rate on the continent is still below 10 per cent.

” While the two newly recommended drugs, baricitinib and sotrovimab, have been invited for WHO Prequalification, the WHO also kicked against the use of two drugs: ruxolitinib and tofacitinib for severe and critical COVID-19, “The panel of experts developing the guidelines also looked at two other drugs for severe and critical COVID-19: ruxolitinib and tofacitinib.Given their uncertain effects, WHO made a conditional recommendation against their use.Advertisements “The two newly recommended drugs – baricitinib and sotrovimab – have been invited for WHO Prequalification, which assesses the quality, efficacy and safety of priority health products to increase access in lower income countries,” it added..

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