Revealing the evolutionary origin of genomic imprinting

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Revealing the evolutionary origin of genomic imprinting
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Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father. The mechanism behind this phenomenon, known as genomic imprinting, is determined by DNA modifications during egg and sperm production.

Revealing the evolutionary origin of genomic imprinting." ScienceDaily. ScienceDaily, 6 March 2024. <www.sciencedaily.comIMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences. . Revealing the evolutionary origin of genomic imprinting.

Hereditary diseases as well as cancers and cardiovascular diseases may be associated with a phenomenon known as genomic imprinting, in which only the maternally or paternally inherited gene is ... Researchers generated mice with a specific DNA sequence inverted to determine if orientation affects expression of a gene called H19. Expression can also be impacted if the surrounding DNA is altered ...

Mothers leave their mark on their children in many ways - and researchers have discovered a protein called SMCHD1 is involved in this 'imprinting' process. SMCHD1 switches certain genes off, altering ... We inherit half of our genes from each parent. For their function of most genes, it doesn't matter which parent a gene comes from. But this is not true for all genes: about 150 genes are subject to ...

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