Taiwanese team finds key antibodies in Covid-19 patients

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TAIPEI, April 8 (The China Post/ANN) — A Taiwanese research team has produced 25 human monoclonal antibodies based on antibody gene segments from three patients infected with the COVID-19 coronavirus.

Huang Kuan-ying , a resident physician at Chang Gung Memorial Hospital who led the research team, told the press Tuesday that the achievement could facilitate the development of not only rapid screening kits but also medication that targets the virus.

The mAbs, made based on antibodies in B cells of the patients, are 13 strains targeting the spike protein of the coronavirus and 12 strains targeting the nucleocapsid protein of the virus. Since the antibodies can identify the virus, they are useful in two areas, including the development and production of rapid testing agents, Huang said, and if such antibody testing agents react to tissue samples containing the virus, they can show the result in a minimum of 30 minutes.

His team found that there is one particular strain among the 13 S-targeting mAbs that has the ability to block the paths that the new coronavirus can use to invade the body, Huang said.

 

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