For those scared of needles, researchers are working on Covid-19 vaccines that can be sprayed into your nose or popped into your mouth. — AFP"The upper respiratory tract is an initial site of SARS-CoV-2 infection, and for many individuals, remains the primary site of virus replication," explain researchers and immunologists in the"An ideal Covid-19 vaccine should reduce upper respiratory tract virus replication and block transmission, as well as protect against severe disease.
"Serum IgG elicited by intramuscular vaccination transudates into the lungs and prevents pulmonary infection, but allows infection in the nasal passages and virus shedding."Research into one vaccine, published in the journalThis vaccine is expected to be tested on 80 healthy adults in the coming months.
The 20 or so researchers who have been working on the project since last summer hope to start testing the vaccine on humans at the end of this year, or early next year.This method of administration is still relatively unusual for vaccines, even though it has been used in certain countries, like the US for flu vaccines.
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