Common medication to treat Type 2 diabetes could help prevent ovarian cancer, study suggests

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The study, published in Clinical Cancer Research, shows that scarring of the ovaries occurs with age and the drug metformin may be able to halt that process

Curtis McCloskey poses in this undated handout photo. McCloskey, who was the study's lead author, says he hopes to see scientists go further by giving women metformin for a year to see if the fibrosis goes away.A new Canadian study suggests a common medication to treat people with Type 2 diabetes could help prevent the development of ovarian cancer.

The study, published today in Clinical Cancer Research, shows that scarring of the ovaries occurs with age and the drug metformin may be able to halt that process. Lead author Curtis McCloskey says one of the primary risk factors for the disease is the number of ovulations a woman has throughout her life.He says the ovary is constantly in a state of growth and retraction, and when that happens repeatedly, you can get scarring or fibrosis.McCloskey says most of the ovaries from post-menopausal women were fibrotic.After looking at her medical records, he discovered she had Type 2 diabetes and was taking metformin.

McCloskey says he hopes to see scientists go further by giving women metformin for a year to see if the fibrosis goes away. Our Morning Update and Evening Update newsletters are written by Globe editors, giving you a concise summary of the day’s most important headlines.

 

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