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China frustrated WHO by delaying coronavirus info, despite public praise: sources

China frustrated WHO by delaying coronavirus info, despite public praise: sources

2020-06-02 9:39:00 AM

China frustrated WHO by delaying coronavirus info, despite public praise: sources

Despite the plaudits from the World Health Organization , China sat on releasing the genetic map, or genome, of the virus for more than a week after three different government labs had fully decoded the information.

Coronavirus outbreak: U.S. demands immediate start to WHO reviewChinese law states that research institutes cannot conduct experiments on potentially dangerous new viruses without approval from top health authorities. Although the law is intended to keep experiments safe, it gives top health officials wide-ranging powers over what lower-level labs can or cannot do.

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Story continues below advertisement“If the virologist community had operated with more autonomy….the public would have been informed of the lethal risk of the new virus much earlier,” said Edward Gu, a professor at Zhejiang University, and Li Lantian, a PhD student at Northwestern University, in a paper published in March analyzing the outbreak.

Commission officials later repeated that they were trying to ensure lab safety, and had tasked four separate government labs with identifying the genome at the same time to get accurate, consistent results.By Jan. 3, the Chinese CDC had independently sequenced the virus, according to internal data seen by the Associated Press. The next day, WHO reported on Twitter that investigations were under way into an unusual cluster of pneumonia cases with no deaths in Wuhan, and said it would share “more details as we have them.”

By just after midnight on Jan. 5, a third designated government lab, the Chinese Academy of Medical Sciences, had decoded the sequence and submitted a report — pulling all-nighters to get results in record time, according to a state media interview. Yet even with full sequences decoded by three state labs independently, Chinese health officials remained silent. The WHO reported on Twitter that investigations were under way into an unusual cluster of pneumonia cases with no deaths in Wuhan, and said it would share “more details as we have them.”

READ MORE:Story continues below advertisementMeanwhile, at the Chinese CDC, gaps in coronavirus expertise proved a problem.For nearly two weeks, Wuhan reported no new infections, as officials censored doctors who warned of suspicious cases. Meanwhile, researchers found the new coronavirus used a distinct spike protein to bind itself to human cells. The unusual protein and the lack of new cases lulled some Chinese CDC researchers into thinking the virus didn’t easily spread between humans — like the coronavirus that casues Middle East respiratory syndrome, or MERS, according to an employee who declined to be identified out of fear of retribution.

Li, the coronavirus expert, said he immediately suspected the pathogen was infectious when he spotted a leaked copy of a sequencing report in a group chat on a SARS-like coronavirus. But the Chinese CDC team that sequenced the virus lacked specialists in the molecular structure of coronaviruses and failed to consult with outside scientists, Li said. Chinese health authorities rebuffed offers of assistance from foreign experts, including Hong Kong scientists barred from a fact-finding mission to Wuhan and an American professor at a university in China.

On Jan. 5, the Shanghai Public Clinical Health Center, led by famed virologist Zhang Yongzhen, was the latest to sequence the virus. He submitted it to the GenBank database, where it sat awaiting review, and notified the National Health Commission. He warned them that the new virus was similar to SARS and likely infectious.

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“It should be contagious through respiratory passages,” the center said in an internal notice seen by the AP. “We recommend taking preventative measures in public areas.”Story continues below advertisementOn the same day, WHO said that based on preliminary information from China, there was no evidence of significant transmission between humans, and did not recommend any specific measures for travelers.

1:37Coronavirus outbreak: WHO chief says independent review of its pandemic handling to happen soon, promises transparencyCoronavirus outbreak: WHO chief says independent review of its pandemic handling to happen soon, promises transparencyThe next day, the Chinese CDC raised its emergency level to the second highest. Staffers proceeded to isolate the virus, draft lab testing guidelines, and design test kits. But the agency did not have the authority to issue public warnings, and the heightened emergency level was kept secret even from many of its own staff.

By Jan. 7, another team at Wuhan University had sequenced the pathogen and found it matched Shi’s, making Shi certain they had identified a novel coronavirus. But Chinese CDC experts said they didn’t trust Shi’s findings and needed to verify her data before she could publish, according to three people familiar with the matter. Both the National Health Commission and the Ministry of Science and Technology, which oversees Shi’s lab, declined to make Shi available for an interview.

Story continues below advertisementA major factor behind the gag order, some say, was that Chinese CDC researchers wanted to publish their papers first. “They wanted to take all the credit,” said Li Yize, a coronavirus researcher at the University of Pennsylvania.

Internally, the leadership of the Chinese CDC is plagued with fierce competition, six people familiar with the system explained. They said the agency has long promoted staff based on how many papers they can publish in prestigious journals, making scientists reluctant to share data.

As the days went by, even some of the Chinese CDC’s own staff began to wonder why it was taking so long for authorities to identify the pathogen.“We were getting suspicious, since within one or two days you would get a sequencing result,” a lab technician said, declining to be identified for fear of retribution.

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___________On Jan. 8, the Wall Street Journal reported that scientists had identified a new coronavirus in samples from pneumonia patients in Wuhan, pre-empting and embarrassing Chinese officials. The lab technician told the AP they first learned about the discovery of the virus from the Journal.

The article also embarrassed WHO officials. Dr. Tom Grein, chief of WHO’s acute events management team, said the agency looked “doubly, incredibly stupid.” Van Kerkhove, the American expert, acknowledged WHO was “already late” in announcing the new virus and told colleagues that it was critical to push China.

Story continues below advertisementRyan, WHO’s chief of emergencies, was also upset at the dearth of information.READ MORE:Trump tells WHO he’ll make funding freeze permanent unless ‘improvements’ are made“The fact is, we’re two to three weeks into an event, we don’t have a laboratory diagnosis, we don’t have an age, sex or geographic distribution, we don’t have an epi curve,” he complained, referring to the standard graphic of outbreaks scientists use to show how an epidemic is progressing.

After the article, state media officially announced the discovery of the new coronavirus. But even then, Chinese health authorities did not release the genome, diagnostic tests, or detailed patient data that could hint at how infectious the disease was.

By that time, suspicious cases were already appearing across the region.On Jan. 8, Thai airport officers pulled aside a woman from Wuhan with a runny nose, sore throat, and high temperature. Chulalongkorn University professor Supaporn Wacharapluesadee’s team found the woman was infected with a new coronavirus, much like what Chinese officials had described. Supaporn partially figured out the genetic sequence by Jan. 9, reported it to the Thai government and spent the next day searching for matching sequences.

But because Chinese authorities hadn’t published any sequences, she found nothing. She could not prove the Thai virus was the same pathogen sickening people in Wuhan.Story continues below advertisement“It was kind of wait and see, when China will release the data, then we can compare,” said Supaporn.

1:24Coronavirus outbreak: Trudeau says Canada supports WHO, but says there ‘needs to be improvements’Coronavirus outbreak: Trudeau says Canada supports WHO, but says there ‘needs to be improvements’On Jan. 9, a 61-year-old man with the virus passed away in Wuhan — the first known death. The death wasn’t made public until Jan. 11.

WHO officials complained in internal meetings that they were making repeated requests for more data, especially to find out if the virus could spread efficiently between humans, but to no avail.“We have informally and formally been requesting more epidemiological information,” WHO’s China representative Galea said. “But when asked for specifics, we could get nothing.”

Emergencies chief Ryan grumbled that since China was providing the minimal information required by international law, there was little WHO could do. But he also noted that last September, WHO had issued an unusual public rebuke of Tanzania for not providing enough details about a worrisome Ebola outbreak.

Story continues below advertisement“We have to be consistent,” Ryan said. “The danger now is that despite our good intent…especially if something does happen, there will be a lot of finger-pointing at WHO.”Ryan noted that China could make a “huge contribution” to the world by sharing the genetic material immediately, because otherwise “other countries will have to reinvent the wheel over the coming days.”

READ MORE:Coronavirus: WHO agrees to independent probe of how it handled pandemicOn Jan. 11, a team led by Zhang, from the Shanghai Public Health Clinical Center, finally published a sequence on virological.org, used by researchers to swap tips on pathogens. The move angered Chinese CDC officials, three people familiar with the matter said, and the next day, his laboratory was temporarily shuttered by health authorities.

Zhang referred a request for comment to the Chinese CDC. The National Health Commission, which oversees the Chinese CDC, declined multiple times to make its officials available for interviews and did not answer questions about Zhang.Supaporn compared her sequence with Zhang’s and found it was a 100% match, confirming that the Thai patient was ill with the same virus detected in Wuhan. Another Thai lab got the same results. That day, Thailand informed the WHO, said Tanarak Plipat, deputy director-general of the Department of Disease Control at Thailand’s Ministry of Public Health.

Story continues below advertisementAfter Zhang released the genome, the Chinese CDC, the Wuhan Institute of Virology and the Chinese Academy of Medical Sciences raced to publish their sequences, working overnight to review them, gather patient data, and send them to the National Health Commission for approval, according to documentation obtained by the AP. On Jan. 12, the three labs together finally published the sequences on GISAID, a platform for scientists to share genomic data.

By then, more than two weeks had passed since Vision Medicals decoded a partial sequence, and more than a week since the three government labs had all obtained full sequences. Around 600 people were infected in that week, a roughly three-fold increase.

1:50Coronavirus outbreak: Chinese President Xi Jinping defends country’s handling of COVID-19Coronavirus outbreak: Chinese President Xi Jinping defends country’s handling of COVID-19Some scientists say the wait was not unreasonable considering the difficulties in sequencing unknown pathogens, given accuracy is as important as speed. They point to the SARS outbreak in 2003 when some Chinese scientists initially — and wrongly — believed the source of the epidemic was chlamydia.

Story continues below advertisement“The pressure is intense in an outbreak to make sure you’re right,” said Peter Daszak, president of the EcoHealthAlliance in New York. “It’s actually worse to go out to go to the public with a story that’s wrong because the public completely lose confidence in the public health response.”

Still, others quietly question what happened behind the scenes.Infectious diseases expert John Mackenzie, who served on a WHO emergency committee during the outbreak, praised the speed of Chinese researchers in sequencing the virus. But he said once central authorities got involved, detailed data trickled to a crawl.

“There certainly was a kind of blank period,” Mackenzie said. “There had to be human to human transmission. You know, it’s staring at you in the face… I would have thought they would have been much more open at that stage.”_________________On Jan. 13, WHO announced that Thailand had a confirmed case of the virus, jolting Chinese officials.

The next day, in a confidential teleconference, China’s top health official ordered the country to prepare for a pandemic, calling the outbreak the “most severe challenge since SARS in 2003”, as the AP previously reported. Chinese CDC staff across the country began screening, isolating, and testing for cases, turning up hundreds across the country.

READ MORE:China’s president pledges $2B over two years to help with COVID-19 responseStory continues below advertisementYet even as the Chinese CDC internally declared a level one emergency, the highest level possible, Chinese officials still said the chance of sustained transmission between humans was low.

WHO went back and forth. Van Kerkhove said in a press briefing that “it is certainly possible there is limited human-to-human transmission.” But hours later, WHO seemed to backtrack, and tweeted that “preliminary investigations conducted by the Chinese authorities have found no clear evidence of human-to-human transmission” – a statement that later became fodder for critics.

A high-ranking official in WHO’s Asia office, Dr. Liu Yunguo, who attended medical school in Wuhan, flew to Beijing to make direct, informal contacts with Chinese officials, recordings show. Liu’s former classmate, a Wuhan doctor, had alerted him that pneumonia patients were flooding the city’s hospitals, and Liu pushed for more experts to visit Wuhan, according to a public health expert familiar with the matter.

On Jan. 20, the leader of an expert team returning from Wuhan, renowned government infectious diseases doctor Zhong Nanshan, declared publicly for the first time that the new virus was spreading between people. Chinese President Xi Jinping called for the “timely publication of epidemic information and deepening of international cooperation.”

Despite that directive, WHO staff still struggled to obtain enough detailed patient data from China about the rapidly evolving outbreak. That same day, the U.N. health agency dispatched a small team to Wuhan for two days, including Galea, the WHO representative in China.

Story continues below advertisementTrump levels sweeping diplomatic penalties against ChinaTrump levels sweeping diplomatic penalties against ChinaThey were told about a worrying cluster of cases among more than a dozen doctors and nurses. But they did not have “transmission trees” detailing how the cases were connected, nor a full understanding of how widely the virus was spreading and who was at risk.

In an internal meeting, Galea said their Chinese counterparts were “talking openly and consistently” about human-to-human transmission, and that there was a debate about whether or not this was sustained. Galea reported to colleagues in Geneva and Manila that China’s key request to WHO was for help “in communicating this to the public, without causing panic.”

On Jan. 22, WHO convened an independent committee to determine whether to declare a global health emergency. After two inconclusive meetings where experts were split, they decided against it — even as Chinese officials ordered Wuhan sealed in the biggest quarantine in history. The next day, WHO chief Tedros publicly described the spread of the new coronavirus in China as “limited.”

Story continues below advertisementFor days, China didn’t release much detailed data, even as its case count exploded. Beijing city officials were alarmed enough to consider locking down the capital, according to a medical expert with direct knowledge of the matter.

On Jan. 28, Tedros and top experts, including Ryan, made an extraordinary trip to Beijing to meet President Xi and other senior Chinese officials. It is highly unusual for WHO’s director-general to directly intervene in the practicalities of outbreak investigations. Tedros’ staffers had prepared a list of requests for information.

READ MORE:China supports ‘inclusive review’ of coronavirus response while pointing finger at U.S.“It could all happen and the floodgates open, or there’s no communication,” Grein said in an internal meeting while his boss was in Beijing. “We’ll see.”At the end of Tedros’ trip, WHO announced China had agreed to accept an international team of experts. In a press briefing on Jan. 29, Tedros heaped praise on China, calling its level of commitment “incredible.”

The next day, WHO finally declared an international health emergency. Once again, Tedros thanked China, saying nothing about the earlier lack of cooperation. Read more: Globalnews.ca »

It is time for Canadians to help Trudeau win his UN Seat. Help the Trudeau Islamist in Canada show their true love for the people of Humanity. Starting in 2021 with all Muslims in Canada marching hand in hand with Gays and Trudeau so the entire world to see the true Islam. Ok, so now WHO has a problem with China Too little too late. defundWHO

WHO and DrTedros are obviously manipulated or even bribed by CCP China. They are sacrificing global health for their own interests and power. They must be held accountable and heavily punished for causing the WuhanVirus pandemic. WhoLiedPeopleDied COVID19 ChinaVirus If everyone were noticed about COVID19 early and be cautious about it we won't have to go lock down...school and work can be continued as normal

That's filtered if not fabricated information and should be taken with a grain of salt. For instance, the WHO remain anti-Taiwan due to China's influence. Praising China in their hopes of obtaining information? Nobody actually believes that rubbish but fools Remember? huh wow you are losing buddy China lied People died

China bad. However, WHO worse by not telling us China was bad. Heaping praise where the opposite was merited was not an incentive and mislead the rest of the world. Thousands of lives were lost. Main purpose for WHO was not realized. Disband. Hmmm catch up, that's old news Fellow Canadians. Realize right now Global News is a propaganda arm of the CCP Chinese Communist Party who have been dividing western democracies into right vs left, gay vs straight, men vs women as an act of war because as a united front we are much stronger opponent.

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Escalating China tensions could become an obstacle for U.S. stock rallyEscalating China tensions could become an obstacle for U.S. stock rally GlobeInvestor globeinvestor Trump would screw up an negotiation with God for sure. globeinvestor Not to mention riots in US cities, a pandemic, an unemployment rate in double digits, a lack of leadership, and the failure of the American president as president. But, if the DJIA goes up today, or even this week, it’s obvious it doesn’t reflect reality. The rich win again. globeinvestor Stop buying made in China Stop buying in chinese stores Stop eating in chinese restaurants Boycott everything from China

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