World first melanoma success in Australia prompts new trial

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Charles Hanna had exhausted all treatments for his cancer, but tumours in his upper abdomen have now vanished. 9News

Molecular testing revealed Mr Hanna had a genetic mutation called PALB2, part of the family of mutations linked to breast and ovarian cancers."It's very pleasing to see how much the melanomas have shrunk and stayed shrunk for at least six months now," Professor Joshua said.

The drug exploits a weakness in the tumour's DNA, blocking the cancer's ability to repair any damage. "As far as we know, Charles is one of the first five people in the world who's had their melanoma treated with these breast cancer and ovarian cancer drugs," Professor Joshua said.

 

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